Michael Turchin

Institute for Genomic Health, Mount Sinai

Publications

  • Turchin MC, Smit RAJ, Choi SW, Belbin GM, Hoggart C, Guindo M, Wang Z, Preuss M, Murphy B, Cho JH, Do R, Loos RJF, O’Reilly PF, Abul-Husn NS, and Kenny EE. 2021. Implementing and evaluating a trans-ancestry LDL-c PRS to predict hypercholesterolemia in a diverse, EHR-embedded biobank. In Preparation.
  • Belbin GM, Rutledge S, Dodatko T, Cullina S, Turchin MC, Kohli S, Torre D, Yee M-C, Gignoux CR, Abul-Husn NS, Houten SM, and Kenny EE. 2021. Using health systems data to uncover a monogenic form of liver disease in Puerto Ricans. medRxiv. https://www.medrxiv.org/content/10.1101/2021.03.31.21254662v1.full. [preprint]
  • Turchin MC, Darnell G, Crawford L, and Ramachandran S. 2020. Pathway Analysis within Multiple Human Ancestries Reveals Novel Signals for Epistasis in Complex Traits. bioRxiv. https://www.biorxiv.org/content/10.1101/2020.09.24.312421v1. [preprint]
  • Turchin MC and Stephens M. 2019. Bayesian multivariate reanalysis of large genetic studies identifies many novel associations. PLOS Genetics. 15(10): e1008431. [preprint] [abs] [pub] [software]
  • Sohail M*, Maier RM*, Ganna A, Bloemendal A, Martin AR, Turchin MC, Chiang CWK, Hirschhorn JN, Daly M, Patterson N, Neale B, Mathieson I, Reich D, and Sunyaev SR. 2019. Signals of polygenic adaptation on height have been overestimated due to uncorrected population structure in genome-wide association studies. eLife. 8, e39702. [preprint] [abs] [pub]
  • Simons YB*, Turchin MC*, Pritchard JK, and Sella G. 2014. The deleterious mutation load is insensitive to recent population history. Nature Genetics. 46: 220-224 [abs] [pub] [supp]
  • Turchin MC*, Charleston CWK*, Palmer CD, Sankararaman S, Reich D, GIANT Consortium, and Hirschhorn JN. 2012. Evidence of widespread selection on standing variation in Europe at height-associated SNPs. Nature Genetics. 44(9): 1015-9 [abs] [pub] [supp]
  • Turchin MC and Hirschhorn JN. 2012. Gencrypt: One-way cryptographic hashes to identify overlapping individuals. Bioinformatics. 28(6): 886-8 [abs] [pub] [supp] [software]
  • Wong AW, Turchin M, Wolfner MF, and Aquadro CF. 2012. Temporally variable selection on proteolysis-related reproductive tract proteins in Drosophila. Molecular Biology and Evolution. 29(1): 229-38 [abs] [pub] [supp]
  • Dauber A*, Yongguo L*, Turchin MC, Chiang CWK, Meng YA, Demerath EW, Patel SR, Rich SS, Rotter JI, Schreiner PJ, Wilson JG, Yiping S, Wu B, and Hirschhorn JN. 2011. Genome-wide association of copy number variation reveals an association between short stature and the presence of low frequency genomic deletions. American Journal of Human Genetics. 89(6): 751-9 [abs] [pub] [supp]
  • Lango AH, Estrada K, Lettre G, Berndt SI, Weedon MN, Rivadeneira F, Willer CJ, et al. 2010. Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature. 467(7317): 832-8 [abs] [pub] [supp]
  • Wong AW, Turchin MC, Wolfner MF, and Aquadro CF. 2008. Evidence for positive selection on Drosophila melanogaster seminal fluid protease homologs. Molecular Biology and Evolution. 25(3): 497-506 [abs] [pub]

* indicates these authors have contributed equally


Teaching and Professional Services

2014 Winter        ECEV 3560: Principles of Population Genetics I (TA)
2013 Fall             HGEN 4700: Human Genetics I (TA)
2013 Winter        ECEV 3560: Principles of Population Genetics I (TA)
2012 Fall             MGCB/HGEN 3140: Genetic Analysis of Model Organisms (TA)

2013-15              Novembre-He-Stephens Lab Meeting Coordinator (UChicago)
2013-15              Student Representative, Department of Human Genetics (UChicago)

2015-19              American Society of Human Genetics DNA Day Essay Contest (Judge)
2014-15,17          Chicago Area Undergraduate Research Symposium (Judge)
2019                   Rhode Island Science and Engineering Fair (Judge)
2019                   Doctoral Dissertation Enhancement Grant (DDEG) Evaluation Panel, Department of                           Ecology and Evolutionary Biology, Brown University (Panelist)

Reviewer             Genetics, Human Molecular Genetics, Nature Communications, PLOS Genetics,
                          Scientific Reports


Selected Awards, Grants, and Fellowships

2018,19               BioMed Postdoc Travel Award (Brown)
2016–17              NIH/NIAID F31 NRSA Predoctoral Training Fellowship (UChicago)
2015–16              ITM/NIH CTSA TL1 Training Grant (UChicago)
2013                   NSF Graduate Research Fellowship Program – Honorable Mention (UChicago)
2011–14              NIH T32 Genetics and Regulation Training Grant (UChicago)
2011                   Pauley Fellowship (UCLA; Declined)
2008                   S. Ann and Robert R. Morley Student Research Grant (Cornell)
2007                   Howard Hughes Summer Research Program in Biology (Cornell)


Selected Conference and Meeting Presentations

2020                   International Conference of Quantitative Genetics 6 (Talk; Postponed due                           to COVID-19)
2020                   The Allied Genetics Conference – PEQG (Talk; Canceled due to COVID-19)
2019                   Probabilistic Modeling in Genomics – Aussois (Talk)
2017                   Department of Computer Science, Princeton University (Seminar)
2017                   Big Data Institute, Oxford University (Seminar)
2017                   Department of Genetics, Perelman School of Medicine, University of                           Pennsylvania (Seminar)
2017                   Gordon Research Seminar – Quantitative Genetics and Genomics (Talk)
2016                   Probabilistic Modeling in Genomics – Oxford University (Talk)
2011                   The Broad Institute: Program in Medical and Population Genetics (Seminar)
2011                   Cold Spring Harbor Labs – Biology of Genomes (Talk)


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