Institute for Genomic Health, Mount Sinai
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Welcome to my research homepage. I am currently a Postdoctoral Fellow with Eimear Kenny in the Institute for Genomic Health at the Icahn School of Medicine at Mount Sinai. My research focuses on understanding the genetic architecture and evolution of complex traits in diverse human populations. To reach these ends, I conduct both basic and translational research through the development and application of population, computational, and statistical genetics methods. The questions I pursue cross the boundaries of population, medical, and evolutionary genomics.
Current projects include:
- Developing and implementing polygenic risk scores in diverse human populations
- Understanding how to conduct electronic health records-based genomic research in diverse human populations
- Conducting pathway and epistatic analyses for complex traits in diverse human populations
- Identifying signals of polygenic adaptation of height in European populations
Recent and past projects include:
- Conducting Bayesian multivariate reanalyses of large-scale GWAS summary statistics
- Investigating rare-variant associations with human HIV-infection using targeted gene-exome sequencing data
- Investigating and comparing the deleterious mutation load between European and African-American populations
- Determing the genetic architecture of human height
- Identifying signals of positive selection in Drosophila melanogaster reproductive proteins
My CV can be found here. Past research experiences include finishing a postdoctoral position with the Ramachandran Lab at Brown University, completing my PhD in Human Genetics with the Stephens Lab while a NRSA Predoctoral Fellow at the University of Chicago, working in the Pritchard Lab (50/50 with Stephens Lab) prior to its move to Stanford, the Hirschhorn Lab at Children's Hospital Boston prior to graduate school, and the Aquadro Lab at Cornell University while receiving my BS.
News:
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